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Effects of Orexin Gene Transfer in the Dorsolateral Pons in Orexin Knockout Mice

STUDY OBJECTIVES: Narcolepsy is a sleep disorder characterized by loss of orexin neurons. Previously, our group demonstrated that transfer of the orexin gene into surrogate neurons in the lateral hypothalamus and the zona incerta significantly reduced cataplexy bouts in the orexin-ataxin-3 mice mode...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Blanco-Centurion, Carlos, Liu, Meng, Konadhode, RodaRani, Pelluru, Dheeraj, Shiromani, Priyattam J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Associated Professional Sleep Societies, LLC 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524540/
https://ncbi.nlm.nih.gov/pubmed/23288969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5665/sleep.2296
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