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Expression and Activity of Fyn Mediate Proliferation and Blastic Features of Chronic Myelogenous Leukemia
The BCR-ABL1 oncogene is a tyrosine kinase that activates many signaling pathways, resulting in the induction of chronic myeloid leukemia (CML). Kinase inhibitors, such as imatinib, have been developed for the treatment of CML; however, the terminal, blast crisis phase of the disease remains a clini...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3524192/ https://ncbi.nlm.nih.gov/pubmed/23284724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051611 |
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