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Oxidative Stress Promotes Transcriptional Up-regulation of Fyn in BCR-ABL1-expressing Cells

Signaling initiated by the BCR-ABL1 kinase causes chronic myelogenous leukemia (CML). Recently, we reported that expression of Fyn, a Src kinase, is heightened in CML cells and patient specimens and confers in vitro and in vivo proliferative advantages. Fyn is regulated by redox, and because BCR-ABL...

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Detalhes bibliográficos
Main Authors: Gao, Yin, Howard, Adrienne, Ban, Kechen, Chandra, Joya
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652262/
https://ncbi.nlm.nih.gov/pubmed/19131339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804801200
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