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BCR-ABL1 mediates up-regulation of Fyn in chronic myelogenous leukemia
Chronic myelogenous leukemia (CML) invariably progresses to blast crisis, which represents the most proliferative phase of the disease. The BCR-ABL1 oncogene stimulates growth and survival pathways by phosphorylating numerous substrates, including various Src family members. Here we describe up-regu...
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| Main Authors: | , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Hematology
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2254539/ https://ncbi.nlm.nih.gov/pubmed/18180382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-091769 |
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