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Inhibition of the NADPH oxidase regulates HO-1 expression in chronic myeloid leukemia

BACKGROUND: Patients with blast crisis phase chronic myelogeneous leukemia (CML) have poor response to tyrosine kinase inhibitors designed to inhibit the BCR-ABL1 oncogene. Recent work has shown that heme oxygenase 1 (HO-1) expression is increased in BCR-ABL1 expressing cells and that inhibition of...

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Detalhes bibliográficos
Main Authors: Singh, Melissa M., Irwin, Mary E., Gao, Yin, Ban, Kechen, Shi, Ping, Arlinghaus, Ralph B., Amin, Hesham M., Chandra, Joya
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297684/
https://ncbi.nlm.nih.gov/pubmed/22139798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.26621
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