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Inhibition of the NADPH oxidase regulates HO-1 expression in chronic myeloid leukemia
BACKGROUND: Patients with blast crisis phase chronic myelogeneous leukemia (CML) have poor response to tyrosine kinase inhibitors designed to inhibit the BCR-ABL1 oncogene. Recent work has shown that heme oxygenase 1 (HO-1) expression is increased in BCR-ABL1 expressing cells and that inhibition of...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3297684/ https://ncbi.nlm.nih.gov/pubmed/22139798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.26621 |
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