Adenosine A(2A) receptor activation reduces recurrence and mortality from Clostridium difficile infection in mice following vancomycin treatment

BACKGROUND: Activation of the A(2A) adenosine receptor (A(2A)AR) decreases production of inflammatory cytokines, prevents C. difficile toxin A-induced enteritis and, in combination with antibiotics, increases survival from sepsis in mice. We investigated whether A(2A)AR activation improves and A(2A)...

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Autori principali: Li, Yuesheng, Figler, Robert A, Kolling, Glynis, Bracken, Tara C, Rieger, Jayson, Stevenson, Ralph W, Linden, Joel, Guerrant, Richard L, Warren, Cirle Alcantara
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523970/
https://ncbi.nlm.nih.gov/pubmed/23217055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-12-342
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