Effects of adenosine A(2A )receptor activation and alanyl-glutamine in Clostridium difficile toxin-induced ileitis in rabbits and cecitis in mice

BACKGROUND: Severe Clostridium difficile toxin-induced enteritis is characterized by exuberant intestinal tissue inflammation, epithelial disruption and diarrhea. Adenosine, through its action on the adenosine A(2A )receptor, prevents neutrophillic adhesion and oxidative burst and inhibits inflammat...

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Detalhes bibliográficos
Main Authors: Warren, Cirle Alcantara, Calabrese, Gina M, Li, Yuesheng, Pawlowski, Sean W, Figler, Robert A, Rieger, Jayson, Ernst, Peter B, Linden, Joel, Guerrant, Richard L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323464/
https://ncbi.nlm.nih.gov/pubmed/22264229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-12-13
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