Contribution of Adenosine A(2B) Receptors in Clostridium difficile Intoxication and Infection

Clostridium difficile toxins A (TcdA) and B (TcdB) induce a pronounced systemic and intestinal inflammatory response. A(2B) adenosine receptors (A(2B)ARs) are the predominant adenosine receptors in the intestinal epithelium. We investigated whether A(2B)ARs are upregulated in human intestinal cells...

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Autores principales: Warren, Cirle A., Li, Yuesheng, Calabrese, Gina M., Freire, Rosemayre S., Zaja-Milatovic, Snjezana, van Opstal, Edward, Figler, Robert A., Linden, Joel, Guerrant, Richard L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
Materias:
Bacterial Infections
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497433/
https://ncbi.nlm.nih.gov/pubmed/23045479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00782-12
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