Glutamine and Alanyl-Glutamine Increase RhoA Expression and Reduce Clostridium difficile Toxin-A-Induced Intestinal Epithelial Cell Damage

Clostridium difficile is a major cause of antibiotic-associated colitis and is associated with significant morbidity and mortality. Glutamine (Gln) is a major fuel for the intestinal cell population. Alanyl-glutamine (Ala-Gln) is a dipeptide that is highly soluble and well tolerated. IEC-6 cells wer...

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Detalhes bibliográficos
Main Authors: Santos, Ana A. Q. A., Braga-Neto, Manuel B., Oliveira, Marcelo R., Freire, Rosemeire S., Barros, Eduardo B., Santiago, Thiago M., Rebelo, Luciana M., Mermelstein, Claudia, Warren, Cirle A., Guerrant, Richard L., Brito, Gerly A. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591182/
https://ncbi.nlm.nih.gov/pubmed/23484083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/152052
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