Inhibition of Glutamate Carboxypeptidase II (GCPII) activity as a treatment for cognitive impairment in multiple sclerosis

Half of all patients with multiple sclerosis (MS) experience cognitive impairment, for which there is no pharmacological treatment. Using magnetic resonance spectroscopy (MRS), we examined metabolic changes in the hippocampi of MS patients, compared the findings to performance on a neurocognitive te...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Rahn, Kristen A., Watkins, Crystal C., Alt, Jesse, Rais, Rana, Stathis, Marigo, Grishkan, Inna, Crainiceau, Ciprian M., Pomper, Martin G., Rojas, Camilo, Pletnikov, Mikhail V., Calabresi, Peter A., Brandt, Jason, Barker, Peter B., Slusher, Barbara S., Kaplin, Adam I.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2012
נושאים:
Biological Sciences
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523869/
https://ncbi.nlm.nih.gov/pubmed/23169655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209934109
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