Conditionally reprogrammed cells represent a stem-like state of adult epithelial cells

The combination of irradiated fibroblast feeder cells and Rho kinase inhibitor, Y-27632, conditionally induces an indefinite proliferative state in primary mammalian epithelial cells. These conditionally reprogrammed cells (CRCs) are karyotype-stable and nontumorigenic. Because self-renewal is a rec...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Suprynowicz, Frank A., Upadhyay, Geeta, Krawczyk, Ewa, Kramer, Sarah C., Hebert, Jess D., Liu, Xuefeng, Yuan, Hang, Cheluvaraju, Chaitra, Clapp, Phillip W., Boucher, Richard C., Kamonjoh, Christopher M., Randell, Scott H., Schlegel, Richard
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2012
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523865/
https://ncbi.nlm.nih.gov/pubmed/23169653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213241109
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