Conditional cell reprogramming involves non-canonical β-catenin activation and mTOR-mediated inactivation of Akt

The combination of irradiated fibroblast feeder cells and Rho kinase inhibitor, Y-267362, converts primary epithelial cells growing in vitro into an undifferentiated adult stem cell-like state that is characterized by long-term proliferation. This cell culture method also maintains the proliferation...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Suprynowicz, Frank A., Kamonjoh, Christopher M., Krawczyk, Ewa, Agarwal, Seema, Wellstein, Anton, Agboke, Fadeke A., Choudhury, Sujata, Liu, Xuefeng, Schlegel, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507294/
https://ncbi.nlm.nih.gov/pubmed/28700668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180897
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