Conditional reprogramming and long-term expansion of normal and tumor cells from human biospecimens

Historically, it has been difficult to propagate cells in vitro that are derived directly from human tumors or healthy tissue. However, in vitro preclinical models are essential tools for both the study of basic cancer biology and the promotion of translational research, including drug discovery and...

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Détails bibliographiques
Publié dans:Nat Protoc
Auteurs principaux: Liu, Xuefeng, Krawczyk, Ewa, Suprynowicz, Frank A, Palechor-Ceron, Nancy, Yuan, Hang, Dakic, Aleksandra, Simic, Vera, Zheng, Yun-Ling, Sripadhan, Praathibha, Chen, Chen, Lu, Jie, Hou, Tung-Wei, Choudhury, Sujata, Kallakury, Bhaskar, Tang, Dean G, Darling, Thomas, Thangapazham, Rajesh, Timofeeva, Olga, Dritschilo, Anatoly, Randell, Scott H, Albanese, Christopher, Agarwal, Seema, Schlegel, Richard
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195120/
https://ncbi.nlm.nih.gov/pubmed/28125105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2016.174
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