Conditional reprogramming and long-term expansion of normal and tumor cells from human biospecimens

Historically, it has been difficult to propagate cells in vitro that are derived directly from human tumors or healthy tissue. However, in vitro preclinical models are essential tools for both the study of basic cancer biology and the promotion of translational research, including drug discovery and...

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Vydáno v:Nat Protoc
Hlavní autoři: Liu, Xuefeng, Krawczyk, Ewa, Suprynowicz, Frank A, Palechor-Ceron, Nancy, Yuan, Hang, Dakic, Aleksandra, Simic, Vera, Zheng, Yun-Ling, Sripadhan, Praathibha, Chen, Chen, Lu, Jie, Hou, Tung-Wei, Choudhury, Sujata, Kallakury, Bhaskar, Tang, Dean G, Darling, Thomas, Thangapazham, Rajesh, Timofeeva, Olga, Dritschilo, Anatoly, Randell, Scott H, Albanese, Christopher, Agarwal, Seema, Schlegel, Richard
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195120/
https://ncbi.nlm.nih.gov/pubmed/28125105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2016.174
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