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HPV16 E7 Protein and hTERT Proteins Defective for Telomere Maintenance Cooperate to Immortalize Human Keratinocytes

Previous studies have shown that wild-type human telomerase reverse transcriptase (hTERT) protein can functionally replace the human papillomavirus type 16 (HPV-16) E6 protein, which cooperates with the viral E7 protein in the immortalization of primary keratinocytes. In the current study, we made t...

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Detalhes bibliográficos
Main Authors: Miller, Jonathan, Dakic, Aleksandra, Chen, Renxiang, Palechor-Ceron, Nancy, Dai, Yuhai, Kallakury, Bhaskar, Schlegel, Richard, Liu, Xuefeng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617164/
https://ncbi.nlm.nih.gov/pubmed/23592995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003284
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