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HPV E7 contributes to the telomerase activity of immortalized and tumorigenic cells and augments E6-induced hTERT promoter function

The E6 and E7 proteins of high-risk HPVs are both required for the immortalization of primary human keratinocytes and the maintenance of the malignant phenotype of HPV-positive cancer cell lines. Our previous studies have shown that E6 protein binds Myc protein and that both E6 and Myc associate wit...

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Bibliografski detalji
Glavni autori: Liu, Xuefeng, Roberts, Jeffrey, Dakic, Aleksandra, Zhang, Yiyu, Schlegel, Richard
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716003/
https://ncbi.nlm.nih.gov/pubmed/18367227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.02.025
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