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HPV E6 protein interacts physically and functionally with the cellular telomerase complex
Telomerase activation is critical for the immortalization of primary human keratinocytes by the high-risk HPV E6 and E7 oncoproteins, and this activation is mediated in part by E6-induction of the hTERT promoter. E6 induces the hTERT promoter via interactions with the cellular ubiquitin ligase, E6AP...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2773972/ https://ncbi.nlm.nih.gov/pubmed/19843693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906357106 |
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