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Total Synthesis of Auripyrone A Using a Tandem Non-Aldol Aldol-Paterson Aldol Process as a Key Step

A tandem non-aldol aldol-Paterson aldol generates the polypropionate 12 from the epoxy alcohol 8 and the ketone 9 in only two steps and 74% overall yield as a single diastereomer, due to double stereodifferentiation, where the stereoinduction from the enolate and the α-methyl substituent of the alde...

詳細記述

保存先:
書誌詳細
主要な著者: Jung, Michael E., Salehi-Rad, Ramin
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523744/
https://ncbi.nlm.nih.gov/pubmed/19824033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.200904607
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