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Diastereoselective, Three-Component, Cascade Synthesis of Tetrahydrofurans and Tetrahydropyrans Employing the Tandem Mukaiyama Aldol-Lactonization (TMAL) Process

[Image: see text] A full account of studies leading to the development of a cascade sequence that generates as many as 2 C-C bonds, 1 C-O bond, and three new stereocenters providing substituted tetrahydrofurans (THFs) from simple γ-ketoaldehydes and thiopyridyl ketene acetals is described. The proce...

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Bibliografski detalji
Glavni autori: Mitchell, T. Andrew, Zhao, Cunxiang, Romo, Daniel
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754051/
https://ncbi.nlm.nih.gov/pubmed/19053579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo801604k
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