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Double Diastereoselective, Nucleophile-Catalyzed Aldol Lactonizations (NCAL) Leading to β-Lactone Fused Carbocycles and Extensions to β-Lactone Fused Tetrahydrofurans
[Image: see text] A double diastereoselective variant of the nucleophile catalyzed aldol-lactonization (NCAL) process is described. This strategy delivers β-lactone-fused carbocycles with good to excellent diastereoselectivities using cinchona alkaloid catalysts with enantioenriched aldehyde acids,...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2933739/ https://ncbi.nlm.nih.gov/pubmed/20704184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol101388h |
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