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Double Diastereoselective, Nucleophile-Catalyzed Aldol Lactonizations (NCAL) Leading to β-Lactone Fused Carbocycles and Extensions to β-Lactone Fused Tetrahydrofurans

[Image: see text] A double diastereoselective variant of the nucleophile catalyzed aldol-lactonization (NCAL) process is described. This strategy delivers β-lactone-fused carbocycles with good to excellent diastereoselectivities using cinchona alkaloid catalysts with enantioenriched aldehyde acids,...

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Detalhes bibliográficos
Main Authors: Morris, Kay A., Arendt, Kevin M., Oh, Seong Ho, Romo, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933739/
https://ncbi.nlm.nih.gov/pubmed/20704184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol101388h
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