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Affinity-Based Probes Based on Type II Kinase Inhibitors

Protein kinases are key components of most mammalian signal transduction networks and are therapeutically relevant drug targets. Efforts to study protein kinase function would benefit from new technologies that are able to profile kinases in complex proteomes. Here, we describe active site-directed...

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Détails bibliographiques
Auteurs principaux: Ranjitkar, Pratistha, Perera, Gayani K., Swaney, Danielle, Hari, Sanjay B., Larson, Eric T., Krishnamurty, Ratika, Merritt, Ethan A., Villén, Judit, Maly, Dustin J.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523701/
https://ncbi.nlm.nih.gov/pubmed/23088519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja306035v
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