Polyclonal CD4(+)Foxp3(+) Treg cells induce TGFβ-dependent tolerogenic dendritic cells that suppress the murine lupus-like syndrome

Interplay between Foxp3(+) regulatory T cells (Treg) and dendritic cells (DCs) maintains immunologic tolerance, but the effects of each cell on the other are not well understood. We report that polyclonal CD4(+)Foxp3(+) Treg cells induced ex vivo with transforming growth factor beta (TGFβ) (iTreg) s...

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Detalhes bibliográficos
Main Authors: Lan, Qin, Zhou, Xiaohui, Fan, Huimin, Chen, Maogen, Wang, Julie, Ryffel, Bernhard, Brand, David, Ramalingam, Rajalakshmy, Kiela, Pawel R., Horwitz, David A., Liu, Zhongmin, Zheng, Song Guo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523557/
https://ncbi.nlm.nih.gov/pubmed/22773728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjs040
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