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Carnosol and Carnosic Acids from Salvia officinalis Inhibit Microsomal Prostaglandin E(2) Synthase-1

Prostaglandin E(2) (PGE(2)), the most relevant eicosanoid promoting inflammation and tumorigenesis, is formed by cyclooxygenases (COXs) and PGE(2) synthases from free arachidonic acid. Preparations of the leaves of Salvia officinalis are commonly used in folk medicine as an effective antiseptic and...

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Detalhes bibliográficos
Main Authors: Bauer, Julia, Kuehnl, Susanne, Rollinger, Judith M., Scherer, Olga, Northoff, Hinnak, Stuppner, Hermann, Werz, Oliver, Koeberle, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523389/
https://ncbi.nlm.nih.gov/pubmed/22511203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.193847
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