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Carnosol and Carnosic Acids from Salvia officinalis Inhibit Microsomal Prostaglandin E(2) Synthase-1

Prostaglandin E(2) (PGE(2)), the most relevant eicosanoid promoting inflammation and tumorigenesis, is formed by cyclooxygenases (COXs) and PGE(2) synthases from free arachidonic acid. Preparations of the leaves of Salvia officinalis are commonly used in folk medicine as an effective antiseptic and...

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Bibliografiske detaljer
Main Authors: Bauer, Julia, Kuehnl, Susanne, Rollinger, Judith M., Scherer, Olga, Northoff, Hinnak, Stuppner, Hermann, Werz, Oliver, Koeberle, Andreas
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523389/
https://ncbi.nlm.nih.gov/pubmed/22511203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.193847
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