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CD4 binding determinant mimicry for HIV vaccine design
The immunodominant epitopes expressed by the HIV-1 envelope protein gp120 are hypermutable, defeating attempts to develop an effective HIV vaccine. Targeting the structurally conserved gp120 determinant that binds host CD4 receptors (CD4BD) and initiates infection is a more promising route to vaccin...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3523313/ https://ncbi.nlm.nih.gov/pubmed/23251137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00383 |
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