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CD4 binding determinant mimicry for HIV vaccine design
The immunodominant epitopes expressed by the HIV-1 envelope protein gp120 are hypermutable, defeating attempts to develop an effective HIV vaccine. Targeting the structurally conserved gp120 determinant that binds host CD4 receptors (CD4BD) and initiates infection is a more promising route to vaccin...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3523313/ https://ncbi.nlm.nih.gov/pubmed/23251137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00383 |
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