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Wild type and K897T polymorphisms of the hERG gene: modeling the APD in Caucasians

The presented study aims to assess the possibility of simulating changes in cardiac cell electrophysiology due to K897T polymorphism in the Caucasian population. In the first part of the experiment, the parameters of the equations describing channel gating were fitted to the experimental data. Then,...

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Detalhes bibliográficos
Main Authors: Glinka, Anna, Polak, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: Biomedical Informatics 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523219/
https://ncbi.nlm.nih.gov/pubmed/23251039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630081062
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