Population pharmacokinetics of clindamycin orally and intravenously administered in patients with osteomyelitis

AIMS: This study was performed to describe clindamycin, administered either orally or intravenously, concentration−time courses to patients with osteomyelitis, to study the effects of different covariates on clindamycin pharmacokinetics and to simulate an optimized administration scheme. METHODS: Cl...

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Hlavní autoři: Bouazza, Naïm, Pestre, Vincent, Jullien, Vincent, Curis, Emmanuel, Urien, Saïk, Salmon, Dominique, Tréluyer, Jean-Marc
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2012
Témata:
Pharmacokinetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522810/
https://ncbi.nlm.nih.gov/pubmed/22486719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2012.04292.x
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