Caricamento...

Tuning the Structural Coupling between the Transmembrane and Cytoplasmic Domains of Phospholamban to Control Sarcoplasmic Reticulum Ca(2+)-ATPase (SERCA) Function

Phospholamban (PLN) is the endogenous inhibitor of the sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA), the integral membrane enzyme responsible for 70% of the Ca(2+) shuttling into the SR, inducing cardiac muscle relaxation in humans. Dysfunctions in SERCA:PLN interactions have been implicated a...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Ha, Kim N., Gustavsson, Martin, Veglia, Gianluigi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522752/
https://ncbi.nlm.nih.gov/pubmed/22971924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10974-012-9319-4
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !