Phospholamban Modulates the Functional Coupling between Nucleotide Domains in Ca-ATPase Oligomeric Complexes in Cardiac Sarcoplasmic Reticulum

Oligomeric interactions between Ca-ATPase polypeptide chains and their modulation by phospholamban (PLB) were measured in native cardiac sarcoplasmic reticulum (SR) microsomes. Progressive modification of Lys(514) with fluorescein-5-isothiocyanate (FITC), which physically blocks access to the nucleo...

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Bibliographic Details
Main Authors: Chen, Linda T.L., Yao, Qing, Soares, Thereza A., Squier, Thomas C., Bigelow, Diana J.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765579/
https://ncbi.nlm.nih.gov/pubmed/19191503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8021526
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