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A Dual Reporter Mouse Model of the Human β-Globin Locus: Applications and Limitations
The human β-globin locus contains the β-like globin genes (i.e. fetal γ-globin and adult β-globin), which heterotetramerize with α-globin subunits to form fetal or adult hemoglobin. Thalassemia is one of the commonest inherited disorders in the world, which results in quantitative defects of the glo...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3522686/ https://ncbi.nlm.nih.gov/pubmed/23272095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051272 |
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