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IL-6 signaling blockade increases inflammation but does not affect muscle function in the mdx mouse
BACKGROUND: IL-6 is a pleiotropic cytokine that modulates inflammatory responses and plays critical roles in muscle maintenance and remodeling. In the mouse model (mdx) of Duchenne Muscular Dystrophy, IL-6 and muscle inflammation are elevated, which is believed to contribute to the chronic inflammat...
में बचाया:
| मुख्य लेखकों: | , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
BioMed Central
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3522537/ https://ncbi.nlm.nih.gov/pubmed/22716658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-13-106 |
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