One-year Treatment of Morpholino Antisense Oligomer Improves Skeletal and Cardiac Muscle Functions in Dystrophic mdx Mice

Antisense therapy has been successful to skip targeted dystrophin exon with correction of frameshift and nonsense mutations of Duchenne muscular dystrophy (DMD). Systemic production of truncated but functional dystrophin proteins has been achieved in animal models. Furthermore, phase I/II clinical t...

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Bibliografiske detaljer
Main Authors: Wu, Bo, Xiao, Bin, Cloer, Caryn, Shaban, Mona, Sali, Arpana, Lu, Peijuan, Li, Juan, Nagaraju, Kanneboyina, Xiao, Xiao, Lu, Qi Long
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048192/
https://ncbi.nlm.nih.gov/pubmed/21179007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.288
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