PRECLINICAL DRUG TRIALS IN THE mdx MOUSE: ASSESSMENT OF RELIABLE AND SENSITIVE OUTCOME MEASURES

The availability of animal models for Duchenne muscular dystrophy has led to extensive preclinical research on potential therapeutics. Few studies have focused on reliability and sensitivity of endpoints for mdx mouse drug trials. Therefore, we sought to compare a wide variety of reported and novel...

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Auteurs principaux: SPURNEY, CHRISTOPHER F., GORDISH-DRESSMAN, HEATHER, GUERRON, ALFREDO D., SALI, ARPANA, PANDEY, GOURI S., RAWAT, RASHMI, VAN DER MEULEN, JACK H., CHA, HEE-JAE, PISTILLI, EMIDIO E., PARTRIDGE, TERENCE A., HOFFMAN, ERIC P., NAGARAJU, KANNEBOYINA
Format: Artigo
Langue:Inglês
Publié: 2009
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116326/
https://ncbi.nlm.nih.gov/pubmed/19260102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mus.21211
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