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Dyskeratosis Congenita Dermal Fibroblasts are Defective in Supporting the Clonogenic Growth of Epidermal Keratinocytes

Telomere shortening is associated with cellular senescence and aging. Dyskeratosis congenita (DC) is a premature aging syndrome caused by mutations in genes for telomerase components or telomere proteins. DC patients have very short telomeres and exhibit aging-associated pathologies including epider...

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Detalhes bibliográficos
Main Authors: Buckingham, Erin M., Goldman, Frederick D., Klingelhutz, Aloysius J.
Formato: Artigo
Idioma:Inglês
Publicado em: JKL International LLC 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522509/
https://ncbi.nlm.nih.gov/pubmed/23251848
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