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Body Mass Influences Cortical Bone Mass Independent of Leptin Signaling
Obesity in humans is associated with increased bone mass. Leptin, a hormone produced by fat cells, functions as a sentinel of energy balance, and may mediate the putative positive effects of body mass on bone. We performed studies in male C57Bl/6 wild type (WT) and leptin-deficient ob/ob mice to det...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3522417/ https://ncbi.nlm.nih.gov/pubmed/19095090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2008.10.058 |
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