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Effects of increased hypothalamic leptin gene expression on ovariectomy-induced bone loss in rats
Estrogen deficiency results in accelerated bone turnover with a net increase in bone resorption. Subcutaneous administration of leptin attenuates bone loss in ovariectomized (ovx) rats by reducing bone resorption. However, in addition to its direct beneficial effects, leptin has been reported to hav...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3152665/ https://ncbi.nlm.nih.gov/pubmed/21640774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2011.04.029 |
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