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Effects of increased hypothalamic leptin gene expression on ovariectomy-induced bone loss in rats

Estrogen deficiency results in accelerated bone turnover with a net increase in bone resorption. Subcutaneous administration of leptin attenuates bone loss in ovariectomized (ovx) rats by reducing bone resorption. However, in addition to its direct beneficial effects, leptin has been reported to hav...

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書誌詳細
主要な著者: Jackson, M.A., Iwaniec, U.T., Turner, R.T., Wronski, T.J., Kalra, S.P.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152665/
https://ncbi.nlm.nih.gov/pubmed/21640774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2011.04.029
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