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Crystal Structure of Calmodulin Binding Domain of Orai1 in Complex with Ca(2+)•Calmodulin Displays a Unique Binding Mode
Orai1 is a plasma membrane protein that in its tetrameric form is responsible for calcium influx from the extracellular environment into the cytosol in response to interaction with the Ca(2+)-depletion sensor STIM1. This is followed by a fast Ca(2+)·calmodulin (CaM)-dependent inhibition, resulting f...
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| Hoofdauteurs: | , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Biochemistry and Molecular Biology
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3522297/ https://ncbi.nlm.nih.gov/pubmed/23109337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.380964 |
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