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Identification of N-terminal Residues of Sonic Hedgehog Important for Palmitoylation by Hedgehog Acyltransferase

Sonic Hedgehog (Shh) is a secreted morphogen that regulates embryonic development. After removal of the signal peptide, Shh is processed to the mature, active form through autocleavage and a series of lipid modifications, including the attachment of palmitate. Covalent attachment of palmitate to the...

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書目詳細資料
Main Authors: Hardy, Rayshonda Y., Resh, Marilyn D.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522284/
https://ncbi.nlm.nih.gov/pubmed/23112049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.426833
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