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The Thermodynamic Basis for Viral RNA Detection by the RIG-I Innate Immune Sensor

RIG-I is a cytoplasmic surveillance protein that contributes to the earliest stages of the vertebrate innate immune response. The protein specifically recognizes 5′-triphosphorylated RNA structures that are released into the cell by viruses, such as influenza and hepatitis C. To understand the energ...

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מידע ביבליוגרפי
Main Authors: Vela, Adriana, Fedorova, Olga, Ding, Steve C., Pyle, Anna Marie
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522258/
https://ncbi.nlm.nih.gov/pubmed/23055530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.385146
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