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Structural insights into RNA recognition by RIG-I
Intracellular RIG-I-like receptors (RLRs, including RIG-I, MDA-5, and LGP-2) recognize viral RNAs as pathogen-associated molecular patterns (PAMPs) and initiate an antiviral immune response. To understand the molecular basis of this process, we determined the crystal structure of RIG-I in complex wi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3222294/ https://ncbi.nlm.nih.gov/pubmed/22000018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.09.023 |
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