Structural insights into RNA recognition by RIG-I

Intracellular RIG-I-like receptors (RLRs, including RIG-I, MDA-5, and LGP-2) recognize viral RNAs as pathogen-associated molecular patterns (PAMPs) and initiate an antiviral immune response. To understand the molecular basis of this process, we determined the crystal structure of RIG-I in complex wi...

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Bibliographic Details
Main Authors: Luo, Dahai, Ding, Steve C., Vela, Adriana, Kohlway, Andrew, Lindenbach, Brett D., Pyle, Anna Marie
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222294/
https://ncbi.nlm.nih.gov/pubmed/22000018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.09.023
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