Synthesis and Antibiotic Properties of Chloramphenicol Reduction Products

Analogs of chloramphenicol were prepared for the first time in which the nitro group was replaced by hydroxylamine, nitroso, hydroxamic acid, methyl hydroxamate, and O-acetyl hydroxamate functional groups. These compounds were tested for antibiotic activity in order to determine whether the antibiot...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Corbett, Michael D., Chipko, Bernadette R.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1978
Fag:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352213/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/646341/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.13.2.193
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