Synthesis and Antibiotic Properties of Chloramphenicol Reduction Products

Analogs of chloramphenicol were prepared for the first time in which the nitro group was replaced by hydroxylamine, nitroso, hydroxamic acid, methyl hydroxamate, and O-acetyl hydroxamate functional groups. These compounds were tested for antibiotic activity in order to determine whether the antibiot...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Autores principales:	Corbett, Michael D., Chipko, Bernadette R.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1978
Materias:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352213/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/646341/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.13.2.193
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