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Synthesis and Antibiotic Properties of Chloramphenicol Reduction Products

Analogs of chloramphenicol were prepared for the first time in which the nitro group was replaced by hydroxylamine, nitroso, hydroxamic acid, methyl hydroxamate, and O-acetyl hydroxamate functional groups. These compounds were tested for antibiotic activity in order to determine whether the antibiot...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Corbett, Michael D., Chipko, Bernadette R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1978
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352213/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/646341/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.13.2.193
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