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Synthesis and Antibiotic Properties of Chloramphenicol Reduction Products

Analogs of chloramphenicol were prepared for the first time in which the nitro group was replaced by hydroxylamine, nitroso, hydroxamic acid, methyl hydroxamate, and O-acetyl hydroxamate functional groups. These compounds were tested for antibiotic activity in order to determine whether the antibiot...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Corbett, Michael D., Chipko, Bernadette R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1978
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352213/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/646341/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.13.2.193
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