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Screening of Finnish RAD51C founder mutations in prostate and colorectal cancer patients

BACKGROUND: Rare, heterozygous germline mutations in the RAD51C gene have been found in breast and ovarian cancer families. In the Finnish population, we have identified two founder mutations in RAD51C that increase the risk of ovarian cancer but not breast cancer in the absence of ovarian cancer. R...

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Detalhes bibliográficos
Main Authors: Pelttari, Liisa M, Nurminen, Riikka, Gylfe, Alexandra, Aaltonen, Lauri A, Schleutker, Johanna, Nevanlinna, Heli
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522023/
https://ncbi.nlm.nih.gov/pubmed/23176254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-552
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