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Screening of Finnish RAD51C founder mutations in prostate and colorectal cancer patients
BACKGROUND: Rare, heterozygous germline mutations in the RAD51C gene have been found in breast and ovarian cancer families. In the Finnish population, we have identified two founder mutations in RAD51C that increase the risk of ovarian cancer but not breast cancer in the absence of ovarian cancer. R...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3522023/ https://ncbi.nlm.nih.gov/pubmed/23176254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-552 |
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