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RAD51, XRCC3, and XRCC2 mutation screening in Finnish breast cancer families
Majority of the known breast cancer susceptibility genes have a role in DNA repair and the most important high-risk genes BRCA1 and BRCA2 are specifically involved in the homologous recombination repair (HRR) of DNA double-strand breaks. A central player in HRR is RAD51 that binds DNA at the damage...
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| Pubblicato in: | Springerplus |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer International Publishing
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4404470/ https://ncbi.nlm.nih.gov/pubmed/25918678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40064-015-0880-3 |
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