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The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity
Human chromosome ends are capped by shelterin, a protein complex that protects the natural ends from being recognized as sites of DNA damage and also regulates the telomere-replicating enzyme, telomerase(1–3). Shelterin includes the heterodimeric POT1-TPP1 protein, which binds the telomeric single-s...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3521872/ https://ncbi.nlm.nih.gov/pubmed/23103865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11648 |
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