Host Defense Peptides of Thrombin Modulate Inflammation and Coagulation in Endotoxin-Mediated Shock and Pseudomonas aeruginosa Sepsis

Gram-negative sepsis is accompanied by a disproportionate innate immune response and excessive coagulation mainly induced by endotoxins released from bacteria. Due to rising antibiotic resistance and current lack of other effective treatments there is an urgent need for new therapies. We here presen...

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Hauptverfasser: Kalle, Martina, Papareddy, Praveen, Kasetty, Gopinath, Mörgelin, Matthias, van der Plas, Mariena J. A., Rydengård, Victoria, Malmsten, Martin, Albiger, Barbara, Schmidtchen, Artur
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521733/
https://ncbi.nlm.nih.gov/pubmed/23272096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051313
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